DegronMD

Uniprot ID: P23352

Source protein: Anosmin-1

Source gene: ANOS1

Class: DEG_SCF_FBW7_2

Location: 636:642

E3 ligase: FBXW7

DEGRON score: 0.6731

ASA_SCORE: 56.0286

COIL: 0.5446

CONS_SCORE: 0.44

DSS_SCORE: 0.4283

HELIX: 0.0047

FCONS_SCORE: 0.8428

RIG_SCORE: 0.6851

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q635H	SIDM00495	B-Cell Non-Hodgkin's Lymphoma	GDSC	VLTPGGE	DEG_SCF_FBW7_2	0.3056
p.Q635H	A3-KAW	haematopoietic_and_lymphoid_tissue	COSMIC	VLTPGGE	DEG_SCF_FBW7_2	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P23352	Anosmin-1	DEG_SCF_FBW7_2	636:642	VLTPGGE	FBXW7	0.6731	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons