DegronMD

Uniprot ID: Q7Z7M1

Source protein: Adhesion G-protein coupled receptor D2

Source gene: ADGRD2

Class: LIG_APCC_ABBA_1

Location: 119:124

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7054

ASA_SCORE: 47.3333

COIL: 0.384

CONS_SCORE: 0.4867

DSS_SCORE: 0.4039

HELIX: 0.0343

FCONS_SCORE: 1.0148

RIG_SCORE: 0.8476

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V131M	SIDM00214	Colorectal Carcinoma	GDSC	VLVFDE	LIG_APCC_ABBA_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z7M1	Adhesion G-protein coupled receptor D2	LIG_APCC_ABBA_1	119:124	VLVFDE	APC,CDC20,FZR1	0.7054	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons