DegronMD

Uniprot ID: Q562F6

Source protein: Shugoshin 2

Source gene: SGO2

Class: DEG_APCC_DBOX_1

Location: 1155:1163

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6566

ASA_SCORE: 71.8111

COIL: 0.6106

CONS_SCORE: 0.4007

DSS_SCORE: 0.2526

HELIX: 0.1064

FCONS_SCORE: 1.009

RIG_SCORE: 0.7576

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.K1168E	SIDM00001	Other Blood Cancers	GDSC	VREGLVPLS	DEG_APCC_DBOX_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q562F6	Shugoshin 2	DEG_APCC_DBOX_1	1155:1163	VREGLVPLS	APC,CDC20,FZR1	0.6566	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons