DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
VRIHNE
Uniprot ID:
Q16670
Source protein:
Zinc finger and SCAN domain-containing protein 26
Source gene:
ZSCAN26
Class:
LIG_APCC_ABBA_1
Location:
441:446
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.8698
ASA_SCORE:
80.7
COIL:
0.7012
CONS_SCORE:
0.8084
DSS_SCORE:
0.2876
HELIX:
0.0673
FCONS_SCORE:
1.1074
RIG_SCORE:
0.7626
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ZSCAN26 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of VRIHNE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q16670
Zinc finger and SCAN domain-containing protein 26
LIG_APCC_ABBA_1
441:446
VRIHNE
APC,CDC20,FZR1
0.8698
More...