DegronMD

Uniprot ID: Q9UMX5

Source protein: Neudesin

Source gene: NENF

Class: LIG_APCC_ABBA_1

Location: 44:49

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9692

ASA_SCORE: 71.0833

COIL: 0.6947

CONS_SCORE: 0.5791

DSS_SCORE: 0.5458

HELIX: 0.1772

FCONS_SCORE: 1.0773

RIG_SCORE: 0.7852

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R36H	ACH-000593	Bladder Cancer	CCLE	VRLFTE	LIG_APCC_ABBA_1	0.1111
p.E58G	ACH-000880	Gastric Cancer	CCLE	VRLFTE	LIG_APCC_ABBA_1	0.0833
p.T34I	ACH-000973	Bladder Cancer	CCLE	VRLFTE	LIG_APCC_ABBA_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9UMX5	Neudesin	LIG_APCC_ABBA_1	44:49	VRLFTE	APC,CDC20,FZR1	0.9692	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons