DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
VRNCLRGLG
Uniprot ID:
A6NNC1
Source protein:
Putative POM121-like protein 1-like
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
870:878
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.5475
ASA_SCORE:
62
COIL:
0.2843
CONS_SCORE:
0.456
DSS_SCORE:
0.0026
HELIX:
0.6978
FCONS_SCORE:
1.6528
RIG_SCORE:
0.959
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of VRNCLRGLG
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NNC1
Putative POM121-like protein 1-like
DEG_APCC_DBOX_1
870:878
VRNCLRGLG
APC,CDC20,FZR1
0.5475
More...