DegronMD

Uniprot ID: P78347

Source protein: General transcription factor II-I

Source gene: GTF2I

Class: DEG_SCF_FBW7_1

Location: 701:707

E3 ligase: FBXW7

DEGRON score: 0.9103

ASA_SCORE: 89.7857

COIL: 0.8659

CONS_SCORE: 0.8138

DSS_SCORE: 0.7232

HELIX: 0.0391

FCONS_SCORE: 1.0454

RIG_SCORE: 0.6835

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V691I	DO228454	PRAD	ICGC	VRTPTQT	DEG_SCF_FBW7_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P78347	General transcription factor II-I	DEG_SCF_FBW7_1	701:707	VRTPTQT	FBXW7	0.9103	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons