DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
VRTRLEILE
Uniprot ID:
Q8N0X7
Source protein:
Spartin
Source gene:
SPART
Class:
DEG_APCC_DBOX_1
Location:
88:96
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6757
ASA_SCORE:
67.0111
COIL:
0.0367
CONS_SCORE:
0.349
DSS_SCORE:
0.3811
HELIX:
0.9618
FCONS_SCORE:
1.3345
RIG_SCORE:
0.8406
Degron related mutations and impact score
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Drug responses associated with SPART mutations
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All proteins holding degron of VRTRLEILE
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N0X7
Spartin
DEG_APCC_DBOX_1
88:96
VRTRLEILE
APC,CDC20,FZR1
0.6757
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