DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
VRTRLEILE
Uniprot ID:
Q8N0X7
Source protein:
Spartin
Source gene:
SPART
Class:
DEG_APCC_DBOX_1
Location:
88:96
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6757
ASA_SCORE:
67.0111
COIL:
0.0367
CONS_SCORE:
0.349
DSS_SCORE:
0.3811
HELIX:
0.9618
FCONS_SCORE:
1.3345
RIG_SCORE:
0.8406
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SPART mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of VRTRLEILE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N0X7
Spartin
DEG_APCC_DBOX_1
88:96
VRTRLEILE
APC,CDC20,FZR1
0.6757
More...