DegronMD

Uniprot ID: Q9P281

Source protein: BAH and coiled-coil domain-containing protein 1

Source gene: BAHCC1

Class: DEG_APCC_DBOX_1

Location: 1515:1523

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6392

ASA_SCORE: 73.2111

COIL: 0.4723

CONS_SCORE: 0.3187

DSS_SCORE: 0.4369

HELIX: 0.4721

FCONS_SCORE: 1.1642

RIG_SCORE: 0.8029

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A1524V	SIDM01016	T-Lymphoblastic Leukemia	GDSC	VRTSLGLLC	DEG_APCC_DBOX_1	0.3056
p.P1505R	SIDM01122	Non-Small Cell Lung Carcinoma	GDSC	VRTSLGLLC	DEG_APCC_DBOX_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9P281	BAH and coiled-coil domain-containing protein 1	DEG_APCC_DBOX_1	1515:1523	VRTSLGLLC	APC,CDC20,FZR1	0.6392	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons