DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
VTVTPSSS
Uniprot ID:
Q9H195
Source protein:
Mucin-3B
Source gene:
MUC3B
Class:
DEG_SCF_FBW7_1
Location:
201:208
E3 ligase:
FBXW7
DEGRON score:
0.9452
ASA_SCORE:
90.3625
COIL:
0.9488
CONS_SCORE:
0.4195
DSS_SCORE:
0.5428
HELIX:
0.0087
FCONS_SCORE:
0.9787
RIG_SCORE:
0.7161
Degron related mutations and impact score
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Drug responses associated with MUC3B mutations
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All proteins holding degron of VTVTPSSS
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9H195
Mucin-3B
DEG_SCF_FBW7_1
201:208
VTVTPSSS
FBXW7
0.9452
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