DegronMD - A0FGR9(ESYT3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E866K	TCGA-CV-7568	HNSC	TCGA	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation rewiring degron network	0.1667
p.E866K	DO14160	HNSC	ICGC	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation rewiring degron network	0.1667
p.G857R	DO48367	BLCA	ICGC	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation altering degron motif	0.6457
p.K843E	DO48687	LIRI	ICGC	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation substituting flanking lysine	0.1944
p.E866D	SIDM01175	Other Sarcomas	GDSC	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation rewiring degron network	0.1667
p.E866D	ACH-002309	Sarcoma	CCLE	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation rewiring degron network	0.1667
p.E866D	SW684	soft tissue	COSMIC	RRKELGKVL	DEG_APCC_DBOX_1	852:860	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons