DegronMD - A1E959(ODAM)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G106C	TCGA-5R-AAAM	LIHC	TCGA	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.G106C	DO219549	LIHC	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.V108G	TCGA-BR-A4PD	STAD	TCGA	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1944
p.V108G	DO47831	STAD	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1944
p.Y129C	TCGA-DY-A1DG	READ	TCGA	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.0556
p.Y129C	DO36853	READ	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.0556
p.S124I	TCGA-KD-A5QS	SARC	TCGA	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1944
p.S124I	DO223270	SARC	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1944
p.G122C	TCGA-QK-A6IJ	HNSC	TCGA	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.25
p.G122C	DO50008	HNSC	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.25
p.D109N	TCGA-XF-A9ST	BLCA	TCGA	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.2222
p.D109N	DO223599	BLCA	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.2222
p.G122S	DO223412	CLLE	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.25
p.L111V	DO234199	ESAD	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.2778
p.V126L	DO229031	LICA	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.V126L	DO229035	LICA	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.A103S	DO229041	LICA	ICGC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.0556
p.G106D	SIDM00946	T-Lymphoblastic Leukemia	GDSC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.G106D	ACH-000981	Leukemia	CCLE	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.G106D	DND-41	haematopoietic and lymphoid tissue	COSMIC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1389
p.T115I	SIDM00680	Colorectal Carcinoma	GDSC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation altering degron motif	0.7078
p.T115I	ACH-000957	Colon/Colorectal Cancer	CCLE	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation altering degron motif	0.7078
p.T115I	LS-180	large intestine	COSMIC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation altering degron motif	0.7078
p.M127V	SIDM00505	Pancreatic Carcinoma	GDSC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1111
p.M127V	MIA-PaCa-2	pancreas	COSMIC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1111
p.Q107H	SIDM01124	Non-Small Cell Lung Carcinoma	GDSC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1667
p.Q107H	ACH-000945	Lung Cancer	CCLE	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1667
p.Q107H	NCI-H650	lung	COSMIC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.1667
p.P116Q	SIDM00727	Non-Small Cell Lung Carcinoma	GDSC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation altering degron motif	0.7035
p.P116Q	ACH-000951	Lung Cancer	CCLE	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation altering degron motif	0.7035
p.P116Q	NCI-H2342	lung	COSMIC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation altering degron motif	0.7035
p.P110H	SIDM01173	Rhabdomyosarcoma	GDSC	LQTPPQT	DEG_SCF_FBW7_1	113:119	Mutation rewiring degron network	0.25

Kaplan plot for ODAM in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ODAM

UniProt ID: A1E959

Entrez ID: 54959

Protein name: Odontogenic ameloblast-associated protein (Apin)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ODAM in