FUNCTION: Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7. {ECO:0000269|PubMed:24000165}....
FUNCTION: Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7. {ECO:0000269|PubMed:24000165}.
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GO - Biological processes (BP):
protein polyubiquitination [GO:0000209]...
protein polyubiquitination [GO:0000209]
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GO - Molecular function (MF):
ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]...
ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]
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GO - Cellular component (CC):
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]...
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]
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