DegronMD - A1L168(C20orf202)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S14T	TCGA-BG-A18B	UCEC	TCGA	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation blocking phosphorylation signal	0.75
p.S14T	DO41452	UCEC	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation blocking phosphorylation signal	0.75
p.P7S	TCGA-DD-AADP	LIHC	TCGA	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation rewiring degron network	0.1111
p.P7S	DO52243	LIHC	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation rewiring degron network	0.1111
p.V17L	DO228447	MALY	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation altering degron motif	0.5654
p.V15G	DO218861	SKCA	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation altering degron motif	0.7532
p.P32L	DO229211	THCA	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation rewiring degron network	0.0556
p.R8L	ACH-001853	Bile Duct Cancer	CCLE	VKVTPKNT	DEG_SCF_FBW7_1	15:22	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons