DegronMD

Uniprot ID: A1L168

Source protein: Uncharacterized protein C20orf202

Source gene: C20orf202

Class: DEG_SCF_FBW7_1

Location: 15:22

E3 ligase: FBXW7

DEGRON score: 0.9771

ASA_SCORE: 85.25

COIL: 0.7581

CONS_SCORE: 1

DSS_SCORE: 0.5258

HELIX: 0.0679

FCONS_SCORE: 1.0476

RIG_SCORE: 0.7257

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S14T	TCGA-BG-A18B	UCEC	TCGA	VKVTPKNT	DEG_SCF_FBW7_1	0.75
p.S14T	DO41452	UCEC	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	0.75
p.P7S	TCGA-DD-AADP	LIHC	TCGA	VKVTPKNT	DEG_SCF_FBW7_1	0.1111
p.P7S	DO52243	LIHC	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	0.1111
p.V17L	DO228447	MALY	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	0.5654
p.V15G	DO218861	SKCA	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	0.7532
p.P32L	DO229211	THCA	ICGC	VKVTPKNT	DEG_SCF_FBW7_1	0.0556
p.R8L	ACH-001853	Bile Duct Cancer	CCLE	VKVTPKNT	DEG_SCF_FBW7_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A1L168	Uncharacterized protein C20orf202	DEG_SCF_FBW7_1	15:22	VKVTPKNT	FBXW7	0.9771	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons