DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
NUTM2F
UniProt ID:
A1L443
Entrez ID:
54754
Protein name:
NUT family member 2F
External links:
UniprotKB
HGNC
RefSeq
COSMIC
Please click
HERE
for better display.
Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
...
View more >>
GO - Biological processes (BP):
...
View more >>
GO - Molecular function (MF):
...
View more >>
GO - Cellular component (CC):
...
View more >>
Choose a PDB ID:
Open in full screen with detailed sequence annotations
NUTM2F
Control panel
Show dataset:
All datasets
TCGA
ICGC
COSMIC
CCLE
GDSC
Show Degron:
All sites
Degron
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Add PTM sites
Phosphorylation
Legend: PTM sites
Data table is loading....
AAchange
Cancer
Sample
Mutation type
Dataset
Degron hit
Class
E3 ligase
Source protein
Location
Detail
Mutation
Sample
Cancer
Degron hit
Class
Location
Dataset
Mutation
Sample
Cancer
Dataset
Degron hit
Class
Location
Type
Impact score
p.P179T
TCGA-17-Z031
LUAD
TCGA
PPAAQVAPI
DEG_SIAH_1
161:169
Mutation rewiring degron network
0.0556
p.V170M
TCGA-CA-6717
COAD
TCGA
PPAAQVAPI
DEG_SIAH_1
161:169
Mutation rewiring degron network
0.3056
p.V170M
DO8264
COAD
ICGC
PPAAQVAPI
DEG_SIAH_1
161:169
Mutation rewiring degron network
0.3056
p.A175G
TCGA-IE-A6BZ
SARC
TCGA
PPAAQVAPI
DEG_SIAH_1
161:169
Mutation rewiring degron network
0.1667
p.A175G
DO220159
SARC
ICGC
PPAAQVAPI
DEG_SIAH_1
161:169
Mutation rewiring degron network
0.1667
p.R176G
DO219873
SKCA
ICGC
PPAAQVAPI
DEG_SIAH_1
161:169
Mutation rewiring degron network
0.1389
Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for NUTM2F in
Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc