DegronMD - A2A368(MAGEB16)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S72Y	TCGA-06-5416	GBM	TCGA	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.2778
p.S72Y	DO10880	GBM	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.2778
p.Q66H	TCGA-85-A4JC	LUSC	TCGA	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1111
p.Q66H	DO45429	LUSC	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1111
p.S88N	TCGA-D3-A5GO	SKCM	TCGA	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.0556
p.S88N	DO47419	SKCM	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.0556
p.E82K	TCGA-E7-A7PW	BLCA	TCGA	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.2222
p.E82K	DO219017	BLCA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.2222
p.V64I	TCGA-OL-A5DA	BRCA	TCGA	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.0556
p.V64I	DO44121	BRCA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.0556
p.C69F	TCGA-X7-A8M3	THYM	TCGA	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1944
p.V75I	DO227975	COCA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5965
p.V75I	DO233764	GACA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5965
p.V75I	SIDM00186	Kidney Carcinoma	GDSC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5965
p.V75I	SIDM00858	Osteosarcoma	GDSC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5965
p.V75I	SIDM01157	Other Solid Cancers	GDSC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5965
p.V75I	SIDM01651	Non-Cancerous	GDSC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5965
p.T76I	DO231984	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.7078
p.A74V	DO50970	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5825
p.A74V	SIDM01679	Small Cell Lung Carcinoma	GDSC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5825
p.A74V	ACH-000523	Lung Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation altering degron motif	0.5825
p.S67N	DO52361	LUSC	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1389
p.P65S	DO220857	MELA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.0833
p.P65S	DO220905	MELA	ICGC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.0833
p.S83Y	SIDM01588	Endometrial Carcinoma	GDSC	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1944
p.S83Y	ACH-000993	Endometrial/Uterine Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1944
p.A86D	ACH-000208	Brain Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	74:78	Mutation rewiring degron network	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MAGEB16

UniProt ID: A2A368

Entrez ID: 139604

Protein name: Melanoma-associated antigen B16 (MAGE-B16 antigen)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MAGEB16 in