DegronMD - A2RUR9(CCDC144A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A1356D	TCGA-06-5416	GBM	TCGA	KRSALKDME	DEG_APCC_DBOX_1	1353:1361	Mutation altering degron motif	0.6682
p.A1356D	DO10880	GBM	ICGC	KRSALKDME	DEG_APCC_DBOX_1	1353:1361	Mutation altering degron motif	0.6682
p.K1366E	TCGA-5P-A9K2	KIRP	TCGA	KRSALKDME	DEG_APCC_DBOX_1	1353:1361	Mutation substituting flanking lysine	0.3056
p.K1366E	DO223947	KIRP	ICGC	KRSALKDME	DEG_APCC_DBOX_1	1353:1361	Mutation substituting flanking lysine	0.3056
p.L1364F	SIDM02077	Colorectal Carcinoma	GDSC	KRSALKDME	DEG_APCC_DBOX_1	1353:1361	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons