DegronMD - A6NFN3(RBFOX3)

RBFOX3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T49I	TCGA-BH-A18G	BRCA	TCGA	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation altering degron motif	0.7078
p.T49I	DO3686	BRCA	ICGC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation altering degron motif	0.7078
p.Q52H	TCGA-GM-A2DO	BRCA	TCGA	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation altering degron motif	0.647
p.Q52H	DO2037	BRCA	ICGC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation altering degron motif	0.647
p.E61V	TCGA-OR-A5KB	ACC	TCGA	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation rewiring degron network	0.1111
p.E61K	DO228310	BRCA	ICGC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation rewiring degron network	0.1111
p.P58T	DO228974	LICA	ICGC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation rewiring degron network	0.1944
p.P50T	DO229037	LICA	ICGC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation altering degron motif	0.7031
p.E56K	SIDM00935	Other Solid Cancers	GDSC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation rewiring degron network	0.25
p.H54Q	SIDM00939	Non-Small Cell Lung Carcinoma	GDSC	LYTPAQT	DEG_SCF_FBW7_1	47:53	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc