DegronMD - A6NGG8(PCARE)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S8G	SIDM01090	Colorectal Carcinoma	GDSC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation altering degron motif	0.8104
p.S8G	RKO	large intestine	COSMIC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation altering degron motif	0.8104
p.D9E	SIDM00789	Colorectal Carcinoma	GDSC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation rewiring degron network	0.3056
p.D9E	HCT-15	large intestine	COSMIC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation rewiring degron network	0.3056
p.P5A	SIDM00761	Small Cell Lung Carcinoma	GDSC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation altering degron motif	0.7503
p.P5A	NCI-H196	lung	COSMIC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation altering degron motif	0.7503
p.G18V	SIDM01442	Glioma	GDSC	MGCTPSHS	DEG_SCF_FBW7_1	1:8	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons