DegronMD - A6NGH7(CCDC160)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R5K	TCGA-05-4396	LUAD	TCGA	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.1389
p.R5K	DO23838	LUAD	ICGC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.1389
p.S40I	TCGA-A5-A0GI	UCEC	TCGA	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.1389
p.S40I	DO41807	UCEC	ICGC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.1389
p.K9N	TCGA-AP-A056	UCEC	TCGA	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation substituting flanking lysine	0.3611
p.K9N	DO43971	UCEC	ICGC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation substituting flanking lysine	0.3611
p.S31Y	TCGA-BS-A0UF	UCEC	TCGA	PESSS	DEG_SPOP_SBC_1	29:33	Mutation altering degron motif	0.712
p.S31Y	DO41488	UCEC	ICGC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation altering degron motif	0.712
p.E10K	TCGA-EE-A2GO	SKCM	TCGA	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.2778
p.E10K	DO37823	SKCM	ICGC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.2778
p.R5I	TCGA-EO-A22X	UCEC	TCGA	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.1389
p.R5I	TCGA-EO-A3AV	UCEC	TCGA	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.1389
p.R5I	DO52412	UCEC	ICGC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.1389
p.R5I	DO43907	UCEC	ICGC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.1389
p.S41R	DO19380	KIRC	ICGC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.1111
p.S27Y	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.0833
p.S27Y	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.2778
p.S27Y	ACH-000030	Lung Cancer	CCLE	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.0833
p.S27Y	ACH-000030	Lung Cancer	CCLE	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.2778
p.S27Y	ACH-000779	Lung Cancer	CCLE	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.0833
p.S27Y	ACH-000779	Lung Cancer	CCLE	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.2778
p.S27Y	PC-14	lung	COSMIC	MFTPFFS	DEG_SCF_FBW7_1	12:18	Mutation rewiring degron network	0.0833
p.S27Y	PC-14	lung	COSMIC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation rewiring degron network	0.2778
p.S32Y	SIDM00118	Colorectal Carcinoma	GDSC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation altering degron motif	0.712
p.S32Y	HCC2998	large intestine	COSMIC	PESSS	DEG_SPOP_SBC_1	29:33	Mutation altering degron motif	0.712

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CCDC160

UniProt ID: A6NGH7

Entrez ID: 347475

Protein name: Coiled-coil domain-containing protein 160

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for CCDC160 in