DegronMD - A6NHP3(SPDYE2B)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A87V	DO229213	THCA	ICGC	LAPEPEETWVVEM	DEG_ODPH_VHL_1	86:98	Mutation altering degron motif	0.6936
p.D78E	DBTRG-05MG	central nervous system	COSMIC	LAPEPEETWVVEM	DEG_ODPH_VHL_1	86:98	Mutation rewiring degron network	0.1111
p.D78E	A431	skin	COSMIC	LAPEPEETWVVEM	DEG_ODPH_VHL_1	86:98	Mutation rewiring degron network	0.1111
p.D78E	RXF393	kidney	COSMIC	LAPEPEETWVVEM	DEG_ODPH_VHL_1	86:98	Mutation rewiring degron network	0.1111
p.D78E	DG-75	haematopoietic and lymphoid tissue	COSMIC	LAPEPEETWVVEM	DEG_ODPH_VHL_1	86:98	Mutation rewiring degron network	0.1111
p.D78E	NAMALWA	haematopoietic and lymphoid tissue	COSMIC	LAPEPEETWVVEM	DEG_ODPH_VHL_1	86:98	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons