DegronMD - A6NIN4(RNF227)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A92P	EN	endometrium	COSMIC	PRGGLTEMA	DEG_APCC_DBOX_1	87:95	Mutation altering degron motif	0.7503
p.A92P	TC-YIK	cervix	COSMIC	PRGGLTEMA	DEG_APCC_DBOX_1	87:95	Mutation altering degron motif	0.7503
p.A92P	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PRGGLTEMA	DEG_APCC_DBOX_1	87:95	Mutation altering degron motif	0.7503
p.A104V	BC-1	haematopoietic and lymphoid tissue	COSMIC	PRGGLTEMA	DEG_APCC_DBOX_1	87:95	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons