DegronMD - A6NJJ6(C19orf67)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R96C	DO220484	KICH	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation rewiring degron network	0.1111
p.S83Y	DO228952	LICA	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation altering degron motif	0.6009
p.S83Y	DO229006	LICA	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation altering degron motif	0.6009
p.D85E	DO229019	LICA	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation altering degron motif	0.5647
p.A78E	DO229036	LICA	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation rewiring degron network	0.2778
p.Q94K	DO229038	LICA	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation rewiring degron network	0.1667
p.L82I	DO229045	LICA	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation altering degron motif	0.6063
p.A141V	DO36556	READ	ICGC	PPIY	ITCH	147:150	Mutation rewiring degron network	0.1667
p.V72A	DO38404	STAD	ICGC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation rewiring degron network	0.1111
p.A141T	DO42673	UCEC	ICGC	PPIY	ITCH	147:150	Mutation rewiring degron network	0.1667
p.R81H	SIDM02050	Colorectal Carcinoma	GDSC	PRLSLDTLF	DEG_APCC_DBOX_1	80:88	Mutation altering degron motif	0.8244

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons