MARCHF11
UniProt ID: A6NNE9
Entrez ID: 441061
Protein name: E3 ubiquitin-protein ligase MARCHF11 (EC 2.3.2.27) (Membrane-associated RING finger protein 11) (Membrane-associated RING-CH protein XI) (MARCH-XI) (RING-type E3 ubiquitin transferase MARCHF11)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sort...
FUNCTION: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids. {ECO:0000250|UniProtKB:A6P320}.
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GO - Biological processes (BP):
protein ubiquitination [GO:0016567]...
protein ubiquitination [GO:0016567]
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GO - Molecular function (MF):
transferase activity [GO:0016740]; zinc ion binding [GO:0008270]...
transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
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GO - Cellular component (CC):
cytoplasmic vesicle membrane [GO:0030659]; integral component of membrane [GO:0016021]...
cytoplasmic vesicle membrane [GO:0030659]; integral component of membrane [GO:0016021]
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MARCHF11
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Kaplan plot for MARCHF11 in
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*NOTE: the Kaplan plots were collected from OncoLnc