DegronMD - A6NNL0(NUTM2B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G197R	DO50879	LICA	ICGC	PSTPLVT	DEG_SCF_FBW7_1	182:188	Mutation rewiring degron network	0.0833
p.F181L	DO218857	SKCA	ICGC	PSTPLVT	DEG_SCF_FBW7_1	182:188	Mutation rewiring degron network	0.3056
p.G192D	ACH-000939	Sarcoma	CCLE	PSTPLVT	DEG_SCF_FBW7_1	182:188	Mutation rewiring degron network	0.2222
p.S183R	MFE-319	endometrium	COSMIC	PSTPLVT	DEG_SCF_FBW7_1	182:188	Mutation altering degron motif	0.6316
p.S183C	MFE-319	endometrium	COSMIC	PSTPLVT	DEG_SCF_FBW7_1	182:188	Mutation altering degron motif	0.643
p.T188I	MFE-319	endometrium	COSMIC	PSTPLVT	DEG_SCF_FBW7_1	182:188	Mutation altering degron motif	0.7078

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons