DegronMD - A6QL63(BTBD11)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P393Q	TCGA-17-Z056	LUAD	TCGA	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.3056
p.L389I	TCGA-AG-3892	READ	TCGA	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation altering degron motif	0.6063
p.L389I	DO36394	READ	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation altering degron motif	0.6063
p.S386N	TCGA-FW-A3R5	SKCM	TCGA	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.3056
p.S386N	DO37406	SKCM	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.3056
p.E401K	TCGA-FW-A3R5	SKCM	TCGA	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.0833
p.E401K	DO37406	SKCM	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.0833
p.Q394H	TCGA-IB-7651	PAAD	TCGA	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.2778
p.Q394H	DO228971	LICA	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.2778
p.Q394H	DO46657	PAAD	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.2778
p.G379E	DO50439	ESAD	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.1111
p.D392E	DO223036	ESCA	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation altering degron motif	0.5647
p.V380L	DO228952	LICA	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.1389
p.L381M	DO232224	PBCA	ICGC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.1667
p.P399L	SIDM01060	Melanoma	GDSC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.1389
p.P399L	ACH-000882	Skin Cancer	CCLE	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.1389
p.P399L	IGR-1	skin	COSMIC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.1389
p.G402C	NCI-H1435	lung	COSMIC	LNLHRD	LIG_APCC_ABBA_1	387:392	Mutation rewiring degron network	0.0556

Kaplan plot for BTBD11 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BTBD11

UniProt ID: A6QL63

Entrez ID: 121551

Protein name: Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 (BTB/POZ domain-containing protein 11)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BTBD11 in