DegronMD - A7E2F4(GOLGA8A)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S80L	TCGA-AX-A0J0	UCEC	TCGA	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.S80L	TCGA-D1-A17Q	UCEC	TCGA	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.S80L	TCGA-EY-A1GI	UCEC	TCGA	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.S80L	DO41903	UCEC	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.S80L	DO41211	UCEC	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.S80L	DO41133	UCEC	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.S82F	TCGA-XK-AAIW	PRAD	TCGA	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.3056
p.S82F	DO51407	PRAD	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.3056
p.E73G	DO227987	COCA	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0556
p.R87G	DO51012	LAML	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7568
p.R87G	ACH-000074	Leukemia	CCLE	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7568
p.R87G	ACH-000459	Kidney Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7568
p.R87G	ACH-000507	Gastric Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7568
p.R87G	ACH-000622	Brain Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7568
p.R87G	ACH-000809	Esophageal Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7568
p.D90N	DO229053	LICA	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.25
p.N89K	DO229053	LICA	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.R81W	DO218843	SKCA	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.Q74R	DO229218	THCA	ICGC	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0833
p.P85L	ACH-000177	Prostate Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7582

Kaplan plot for GOLGA8A in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GOLGA8A

UniProt ID: A7E2F4

Entrez ID: 23015

Protein name: Golgin subfamily A member 8A (88 kDa Golgi matrix protein) (GM88) (GM88 autoantigen)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for GOLGA8A in