DegronMD - A8K4G0(CD300LB)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R132G	TCGA-55-7907	LUAD	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2778
p.R132G	DO25396	LUAD	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2778
p.R122H	TCGA-AF-A56N	READ	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.R122H	DO50277	READ	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.A136T	TCGA-AX-A1CE	UCEC	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.1667
p.A136T	DO42280	UCEC	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.1667
p.V138A	TCGA-BR-8680	STAD	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.1111
p.V138A	DO47769	STAD	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.1111
p.T123M	TCGA-DB-A64S	LGG	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	TCGA-FI-A2D0	UCEC	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	TCGA-FW-A3R5	SKCM	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	TCGA-HC-8213	PRAD	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	DO233210	GACA	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	DO44619	LGG	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	DO49812	PRAD	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	DO37406	SKCM	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123M	DO43891	UCEC	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.D134Y	TCGA-DX-A7EU	SARC	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.D134Y	DO220040	SARC	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.R122C	TCGA-FA-8693	DLBC	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.R122C	DO219884	DLBC	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.T123S	TCGA-FW-A3R5	SKCM	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.T123S	DO37406	SKCM	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.E129D	TCGA-HU-A4GU	STAD	TCGA	AASTT	DEG_SPOP_SBC_1	126:130	Mutation altering degron motif	0.6758
p.E129D	DO47849	STAD	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation altering degron motif	0.6758
p.R122S	DO229035	LICA	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.2222
p.T123K	DO229035	LICA	ICGC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.25
p.N136D	SIDM01083	Oral Cavity Carcinoma	GDSC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.1667
p.N136D	SCC-15	upper aerodigestive tract	COSMIC	AASTT	DEG_SPOP_SBC_1	126:130	Mutation rewiring degron network	0.1667

Kaplan plot for CD300LB in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CD300LB

UniProt ID: A8K4G0

Entrez ID: 124599

Protein name: CMRF35-like molecule 7 (CLM-7) (CD300 antigen-like family member B) (CMRF35-A2) (Immune receptor expressed on myeloid cells 3) (IREM-3) (Leukocyte mono-Ig-like receptor 5) (Triggering receptor expressed on myeloid cells 5) (TREM-5) (CD antigen CD300b)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CD300LB in