DegronMD - A8MUX0(KRTAP16-1)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S243G	DO222990	BTCA	ICGC	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation rewiring degron network	0.2222
p.S243G	DO230550	LUSC	ICGC	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation rewiring degron network	0.2222
p.C238W	SIDM01032	Esophageal Squamous Cell Carcinoma	GDSC	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation altering degron motif	0.5889
p.C238W	ACH-000823	Esophageal Cancer	CCLE	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation altering degron motif	0.5889
p.C238W	KYSE-140	oesophagus	COSMIC	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation altering degron motif	0.5889
p.P234S	SIDM00844	Burkitt's Lymphoma	GDSC	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation altering degron motif	0.5641
p.T241P	HCC2998	large intestine	COSMIC	VCPTPTCS	DEG_SCF_FBW7_1	232:239	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons