DegronMD - A8MVS5(HIDE1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E219Q	TCGA-AX-A2IO	UCEC	TCGA	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation altering degron motif	0.5633
p.E219Q	DO40800	UCEC	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation altering degron motif	0.5633
p.E222K	TCGA-EI-6917	READ	TCGA	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation altering degron motif	0.591
p.E222K	DO36881	READ	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation altering degron motif	0.591
p.S213C	TCGA-FX-A3NK	SARC	TCGA	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation altering degron motif	0.7541
p.S213C	DO220120	SARC	ICGC	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation altering degron motif	0.7541
p.F226L	TCGA-FX-A3NK	SARC	TCGA	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation rewiring degron network	0.2778
p.F226L	DO220120	SARC	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation rewiring degron network	0.2778
p.S215F	DO234227	ESAD	ICGC	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation altering degron motif	0.7982
p.R208Q	DO233260	GACA	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation rewiring degron network	0.0556
p.R208Q	DO233260	GACA	ICGC	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation rewiring degron network	0.25
p.R208Q	DO222775	MELA	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation rewiring degron network	0.0556
p.R208Q	DO222775	MELA	ICGC	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation rewiring degron network	0.25
p.C229F	DO229035	LICA	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation rewiring degron network	0.1944
p.S217L	DO231343	THCA	ICGC	PETPEFS	DEG_SCF_FBW7_1	218:224	Mutation rewiring degron network	0.3056
p.S217L	DO231343	THCA	ICGC	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation rewiring degron network	0.2778
p.S215Y	SIDM00281	Other Solid Cancers	GDSC	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation altering degron motif	0.712
p.S215Y	ACH-002100	Skin Cancer	CCLE	PTSTS	DEG_SPOP_SBC_1	211:215	Mutation altering degron motif	0.712

Kaplan plot for HIDE1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

HIDE1

UniProt ID: A8MVS5

Entrez ID: 255809

Protein name: Protein HIDE1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for HIDE1 in