DegronMD - A8TX70(COL6A5)

COL6A5

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L258I	TCGA-A6-5661	COAD	TCGA	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.0833
p.L258I	DO8634	COAD	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.0833
p.Y279S	TCGA-AA-A010	COAD	TCGA	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.1111
p.M277V	TCGA-EY-A2OM	UCEC	TCGA	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.1667
p.M277V	DO43025	UCEC	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.1667
p.M272L	DO225112	BRCA	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.3056
p.R273Q	DO222884	COCA	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.2778
p.R273Q	DO33800	PACA	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.2778
p.R273Q	ACH-000100	Sarcoma	CCLE	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.2778
p.R273Q	ACH-001765	Sarcoma	CCLE	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.2778
p.S263C	DO228937	LICA	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation rewiring degron network	0.2222
p.C271R	DO45237	LIRI	ICGC	VKENC	DEG_APCC_KENBOX_2	267:271	Mutation altering degron motif	0.719

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*NOTE: the Kaplan plots were collected from OncoLnc