DegronMD - B2RXF5(ZBTB42)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H202L	TCGA-2H-A9GL	ESCA	TCGA	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation rewiring degron network	0.2222
p.H202Q	TCGA-DX-A48V	SARC	TCGA	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation rewiring degron network	0.2222
p.H202Q	DO219991	SARC	ICGC	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation rewiring degron network	0.2222
p.V206F	DO229041	LICA	ICGC	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation altering degron motif	0.7068
p.Q208H	DO26427	LUSC	ICGC	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation altering degron motif	0.647
p.P203T	DO229224	THCA	ICGC	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation rewiring degron network	0.25
p.L211I	ACH-000967	Colon/Colorectal Cancer	CCLE	VLQTPLCS	DEG_SCF_FBW7_1	206:213	Mutation altering degron motif	0.6063

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons