DegronMD - B2RXH2(KDM4E)

KDM4E

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E331Q	TCGA-55-A48Y	LUAD	TCGA	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation rewiring degron network	0.2222
p.E331Q	DO26160	LUAD	ICGC	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation rewiring degron network	0.2222
p.L339V	TCGA-A5-A1OH	UCEC	TCGA	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation altering degron motif	0.6765
p.L339V	DO48180	UCEC	ICGC	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation altering degron motif	0.6765
p.R348K	TCGA-E6-A1LX	UCEC	TCGA	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation rewiring degron network	0.1944
p.R348K	DO41020	UCEC	ICGC	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation rewiring degron network	0.1944
p.V342L	DO229037	LICA	ICGC	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation altering degron motif	0.5654
p.E331D	DO229041	LICA	ICGC	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation rewiring degron network	0.2222
p.A340V	ACH-000919	Gastric Cancer	CCLE	HRQDLAIVE	DEG_APCC_DBOX_1	335:343	Mutation altering degron motif	0.5825

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*NOTE: the Kaplan plots were collected from OncoLnc