DegronMD - B4DS77(SHISA9)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F368L	TCGA-L5-A4OU	ESCA	TCGA	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.25
p.L360P	DO24860	LUAD	ICGC	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.3056
p.N353H	DO50720	ORCA	ICGC	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.1111
p.R351S	SIDM02045	Colorectal Carcinoma	GDSC	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.0556
p.L360V	SIDM02071	Esophageal Carcinoma	GDSC	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.3056
p.R351L	SIDM00760	Small Cell Lung Carcinoma	GDSC	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.0556
p.R351L	ACH-000729	Lung Cancer	CCLE	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.0556
p.R351L	NCI-H1963	lung	COSMIC	AYTST	DEG_SPOP_SBC_1	361:365	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons