DegronMD - C9J069(AJM1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S236W	SIDM00614	Hepatocellular Carcinoma	GDSC	LSRTPTPS	DEG_SCF_FBW7_1	235:242	Mutation altering degron motif	0.6763
p.S236W	JHH-7	liver	COSMIC	LSRTPTPS	DEG_SCF_FBW7_1	235:242	Mutation altering degron motif	0.6763
p.T240A	SIDM00451	T-Lymphoblastic Leukemia	GDSC	LSRTPTPS	DEG_SCF_FBW7_1	235:242	Mutation altering degron motif	0.6028
p.T240A	PF-382	haematopoietic and lymphoid tissue	COSMIC	LSRTPTPS	DEG_SCF_FBW7_1	235:242	Mutation altering degron motif	0.6028

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons