DegronMD - C9JTQ0(ANKRD63)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L305S	DO233869	GACA	ICGC	LSPHPE	LIG_APCC_ABBA_1	312:317	Mutation rewiring degron network	0.1389
p.P309L	DO222727	MELA	ICGC	LSPHPE	LIG_APCC_ABBA_1	312:317	Mutation rewiring degron network	0.25
p.P314L	DO222875	MELA	ICGC	LSPHPE	LIG_APCC_ABBA_1	312:317	Mutation altering degron motif	0.6471
p.P320S	DO232519	PBCA	ICGC	LSPHPE	LIG_APCC_ABBA_1	312:317	Mutation rewiring degron network	0.25
p.P320L	DO229216	THCA	ICGC	LSPHPE	LIG_APCC_ABBA_1	312:317	Mutation rewiring degron network	0.25
p.P302T	DO229250	THCA	ICGC	LSPHPE	LIG_APCC_ABBA_1	312:317	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons