DegronMD - D6RIA3(C4orf54)

GO - Biological processes (BP):

GO - Molecular function (MF):

GO - Cellular component (CC):

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Degron hit	Class	E3 ligase	Source protein	Location	Detail
WRADLGEIS	DEG_APCC_DBOX_1	APC,CDC20,FZR1	Uncharacterized protein C4orf54	972:980	More..
IAPPSFDGTTMSF	DEG_ODPH_VHL_1	VHL	Uncharacterized protein C4orf54	1776:1788	More..
PTPPPT	DEG_SCF_FBW7_1	FBXW7	Uncharacterized protein C4orf54	478:483	More..
PQTTS	DEG_SPOP_SBC_1	SPOP	Uncharacterized protein C4orf54	59:63	More..
ATSSS	DEG_SPOP_SBC_1	SPOP	Uncharacterized protein C4orf54	297:301	More..
VPSSS	DEG_SPOP_SBC_1	SPOP	Uncharacterized protein C4orf54	1515:1519	More..
PASST	DEG_SPOP_SBC_1	SPOP	Uncharacterized protein C4orf54	1735:1739	More..
LQPLRGQRR	SCF_FBXL2	FBXL2	Uncharacterized protein C4orf54	114:122	More..

Showing 1 to 8 of 8 entries

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A1744T	SIDM02072	Colorectal Carcinoma	GDSC	PASST	DEG_SPOP_SBC_1	1735:1739	Mutation rewiring degron network	0.1944
p.S73F	SIDM00006	Other Solid Cancers	GDSC	PQTTS	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.0556

Showing 1 to 2 of 2 entries

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons