DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
UBE2Q2L
UniProt ID:
H0YL09
Entrez ID:
100505679
Protein name:
Putative ubiquitin-conjugating enzyme E2Q2-like protein
External links:
UniprotKB
HGNC
RefSeq
COSMIC
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Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
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GO - Biological processes (BP):
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GO - Molecular function (MF):
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GO - Cellular component (CC):
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UBE2Q2L
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AAchange
Cancer
Sample
Mutation type
Dataset
Degron hit
Class
E3 ligase
Source protein
Location
Detail
Mutation
Sample
Cancer
Degron hit
Class
Location
Dataset
Mutation
Sample
Cancer
Dataset
Degron hit
Class
Location
Type
Impact score
p.S42L
SIDM02049
Pancreatic Carcinoma
GDSC
RPIVFKE
LIG_APCC_ABBAyCdc20_2
28:34
Mutation rewiring degron network
0.1111
Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for UBE2Q2L in
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Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc