DegronMD

Uniprot ID: H0YL09

Source protein: Putative ubiquitin-conjugating enzyme E2Q2-like protein

Source gene: UBE2Q2L

Class: LIG_APCC_ABBAyCdc20_2

Location: 28:34

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7592

ASA_SCORE: 80.6143

COIL: 0.5999

CONS_SCORE: 0

DSS_SCORE: 0.406

HELIX: 0.1374

FCONS_SCORE: 0

RIG_SCORE: 0.8223

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S42L	SIDM02049	Pancreatic Carcinoma	GDSC	RPIVFKE	LIG_APCC_ABBAyCdc20_2	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
H0YL09	Putative ubiquitin-conjugating enzyme E2Q2-like protein	LIG_APCC_ABBAyCdc20_2	28:34	RPIVFKE	APC,CDC20,FZR1	0.7592	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons