DegronMD - O00115(DNASE2)

DNASE2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S88R	TCGA-86-8056	LUAD	TCGA	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222
p.S88R	DO24950	LUAD	ICGC	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222
p.S88N	TCGA-A6-2686	COAD	TCGA	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222
p.S88N	DO7828	COAD	ICGC	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222
p.N86S	TCGA-DD-A118	LIHC	TCGA	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.1667
p.N86S	DO22905	LIHC	ICGC	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.1667
p.Q89K	DO229006	LICA	ICGC	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.25
p.S88I	SIDM00386	Ewing's Sarcoma	GDSC	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222
p.S88I	ACH-000391	Bone Cancer	CCLE	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222
p.S88I	MHH-ES-1	bone	COSMIC	FLLYND	LIG_APCC_ABBA_1	92:97	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc