FUNCTION: Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction. {ECO:0000269|PubMed:21949850}....
FUNCTION: Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction. {ECO:0000269|PubMed:21949850}.
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GO - Biological processes (BP):
single fertilization [GO:0007338]; ubiquitin-dependent ERAD pathway [GO:0030433]...
single fertilization [GO:0007338]; ubiquitin-dependent ERAD pathway [GO:0030433]
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GO - Molecular function (MF):
protein-macromolecule adaptor activity [GO:0030674]; ubiquitin binding [GO:0043130]...
protein-macromolecule adaptor activity [GO:0030674]; ubiquitin binding [GO:0043130]
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GO - Cellular component (CC):
endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151]...
endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151]
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