DegronMD - O00305(CACNB4)

CACNB4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D69N	TCGA-D3-A3MR	SKCM	TCGA	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.0556
p.P59S	TCGA-DA-A1HV	SKCM	TCGA	DSYTSRP	CBL_PTK	53:59	Mutation altering degron motif	0.6752
p.S57R	TCGA-DX-A6YS	SARC	TCGA	DSYTSRP	CBL_PTK	53:59	Mutation altering degron motif	0.6316
p.A54E	DO229029	LICA	ICGC	DSYTSRP	CBL_PTK	53:59	Mutation altering degron motif	0.7701
p.D51N	DO47256	SKCM	ICGC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.2778
p.R52W	DO38567	STAD	ICGC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.3056
p.A64S	DO41999	UCEC	ICGC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.1944
p.V64A	SIDM01059	Melanoma	GDSC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.1944
p.V64A	IPC-298	skin	COSMIC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.1944
p.D63N	SIDM01664	Prostate Carcinoma	GDSC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.2222
p.A59T	ACH-000993	Endometrial/Uterine Cancer	CCLE	DSYTSRP	CBL_PTK	53:59	Mutation altering degron motif	0.7139
p.D61E	ACH-001127	Leukemia	CCLE	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.2778
p.D61E	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.2778
p.V46A	IPC-298	skin	COSMIC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.1389
p.D60Y	Mewo	skin	COSMIC	DSYTSRP	CBL_PTK	53:59	Mutation rewiring degron network	0.3056
p.Y57C	JHH-7	liver	COSMIC	DSYTSRP	CBL_PTK	53:59	Mutation altering degron motif	0.7087

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*NOTE: the Kaplan plots were collected from OncoLnc