DegronMD - O00399(DCTN6)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D76Y	TCGA-AP-A1DV	UCEC	TCGA	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.3056
p.D76Y	DO43186	UCEC	ICGC	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.3056
p.G85A	TCGA-BS-A0UF	UCEC	TCGA	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.0556
p.G85A	DO41488	UCEC	ICGC	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.0556
p.D76N	TCGA-E6-A1LX	UCEC	TCGA	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.3056
p.D76N	DO41020	UCEC	ICGC	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.3056
p.D73N	DO233276	GACA	ICGC	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation altering degron motif	0.5821
p.A65V	SIDM00217	Colorectal Carcinoma	GDSC	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.1944
p.A65V	SNU-1040	large intestine	COSMIC	ITPDTE	DEG_SCF_FBW7_2	70:75	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons