DegronMD - O00401(WASL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S449Y	TCGA-86-8073	LUAD	TCGA	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.0833
p.S449Y	DO23624	LUAD	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.0833
p.E455V	TCGA-C5-A7UE	CESC	TCGA	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.25
p.E455V	DO49890	CESC	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.25
p.A470T	TCGA-EO-A22U	UCEC	TCGA	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.1667
p.A470T	DO43755	UCEC	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.1667
p.I467T	TCGA-UZ-A9PV	KIRP	TCGA	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.25
p.I467T	DO219711	KIRP	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.25
p.V468A	DO230334	COCA	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.2222
p.S465L	DO233151	GACA	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.3056
p.T464N	DO228974	LICA	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation altering degron motif	0.8166
p.G453C	DO229211	THCA	ICGC	PPTPAPT	DEG_SCF_FBW7_1	458:464	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons