DegronMD - O00418(EEF2K)

EEF2K

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E436D	TCGA-CA-6718	COAD	TCGA	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.2222
p.E436D	DO7801	COAD	ICGC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.2222
p.N431Y	TCGA-CN-5356	HNSC	TCGA	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.0833
p.N431Y	DO15390	HNSC	ICGC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.0833
p.R448L	TCGA-G2-A2EJ	BLCA	TCGA	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.25
p.R448L	DO554	BLCA	ICGC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.25
p.R433L	DO230342	COCA	ICGC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.1389
p.H432L	DO234336	ESAD	ICGC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.1111
p.S438I	DO229036	LICA	ICGC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation blocking phosphorylation signal	0.7222
p.S438N	SIDM00946	T-Lymphoblastic Leukemia	GDSC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation blocking phosphorylation signal	0.7222
p.S438N	ACH-000981	Leukemia	CCLE	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation blocking phosphorylation signal	0.7222
p.S438N	DND-41	haematopoietic and lymphoid tissue	COSMIC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation blocking phosphorylation signal	0.7222
p.G449S	SIDM00196	Ewing's Sarcoma	GDSC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.2222
p.G449S	EW-22	bone	COSMIC	DSGYPS	DEG_SCF_TRCP1_1	440:445	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc