DegronMD - O00472(ELL2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L445I	TCGA-19-1390	GBM	TCGA	SRTSLETLP	DEG_APCC_DBOX_1	431:439	Mutation rewiring degron network	0.1667
p.I421N	TCGA-55-A490	LUAD	TCGA	SRTSLETLP	DEG_APCC_DBOX_1	431:439	Mutation rewiring degron network	0.0556
p.L435V	TCGA-DG-A2KK	CESC	TCGA	SRTSLETLP	DEG_APCC_DBOX_1	431:439	Mutation altering degron motif	0.6765
p.S431C	TCGA-RS-A6TO	HNSC	TCGA	SRTSLETLP	DEG_APCC_DBOX_1	431:439	Mutation altering degron motif	0.643
p.T430A	ACH-000960	Leukemia	CCLE	SRTSLETLP	DEG_APCC_DBOX_1	431:439	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons