DegronMD - O00555(CACNA1A)

CACNA1A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S2277T	TCGA-DD-AAVP	LIHC	TCGA	APSTS	DEG_SPOP_SBC_1	2270:2274	Mutation rewiring degron network	0.25
p.S2277T	DO52275	LIHC	ICGC	APSTS	DEG_SPOP_SBC_1	2270:2274	Mutation rewiring degron network	0.25
p.A2270D	DO228948	LICA	ICGC	APSTS	DEG_SPOP_SBC_1	2270:2274	Mutation altering degron motif	0.7793
p.T2284A	SIDM01307	Colorectal Carcinoma	GDSC	APSTS	DEG_SPOP_SBC_1	2270:2274	Mutation rewiring degron network	0.0556
p.R2462L	SIDM00690	Head and Neck Carcinoma	GDSC	PRTPRAS	DEG_SCF_FBW7_1	2452:2458	Mutation rewiring degron network	0.2222
p.R2462L	SIDM00142	Endometrial Carcinoma	GDSC	PRTPRAS	DEG_SCF_FBW7_1	2452:2458	Mutation rewiring degron network	0.2222
p.G2275C	ACH-000514	Lung Cancer	CCLE	APSTS	DEG_SPOP_SBC_1	2270:2274	Mutation rewiring degron network	0.3056
p.A2447T	ACH-001375	Pancreatic Cancer	CCLE	PRTPRAS	DEG_SCF_FBW7_1	2452:2458	Mutation rewiring degron network	0.1944
p.P2283T	WM1552C	skin	COSMIC	APSTS	DEG_SPOP_SBC_1	2270:2274	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc