DegronMD - O00566(MPHOSPH10)

MPHOSPH10

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D174N	TCGA-50-5066	LUAD	TCGA	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.1667
p.D174N	DO25040	LUAD	ICGC	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.1667
p.S156N	TCGA-BT-A3PH	BLCA	TCGA	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.1667
p.S156N	DO856	BLCA	ICGC	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.1667
p.D168N	TCGA-CR-5248	HNSC	TCGA	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation altering degron motif	0.6932
p.D168N	DO14694	HNSC	ICGC	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation altering degron motif	0.6932
p.E169K	TCGA-NC-A5HD	LUSC	TCGA	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.3056
p.E169K	DO219184	LUSC	ICGC	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.3056
p.D174H	TCGA-VS-AA62	CESC	TCGA	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.1667
p.D174H	DO219745	CESC	ICGC	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.1667
p.L160M	DO222602	COCA	ICGC	KSPVFSD	LIG_APCC_ABBAyCdc20_2	162:168	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc