DegronMD - O00625(PIR)

PIR

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H112D	TCGA-A8-A09W	BRCA	TCGA	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.0833
p.H112D	DO1476	BRCA	ICGC	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.0833
p.A95V	TCGA-BR-8680	STAD	TCGA	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.2778
p.A95V	DO52674	MALY	ICGC	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.2778
p.A95V	DO47769	STAD	ICGC	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.2778
p.A95V	ACH-001369	Ovarian Cancer	CCLE	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.2778
p.P105T	TCGA-BS-A0TI	UCEC	TCGA	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.2778
p.P105T	DO41608	UCEC	ICGC	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.2778
p.M104V	TCGA-EO-A22U	UCEC	TCGA	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.3056
p.M104V	DO43755	UCEC	ICGC	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.3056
p.C106F	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	RGILHAE	LIG_APCC_ABBAyCdc20_2	97:103	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc